Flavanol-Rich Cocoa and Cerebral Blood Flow

Not Applicable

Completed

• Conditions: Hypertension; Diabetes
• Interventions: Dietary Supplement: cocoa

• Registration Number: NCT00825695
• Lead Sponsor: Brigham and Women's Hospital

Brief Summary

The purpose of the study is to learn whether or not cocoa has a beneficial effect on blood flow to the brain in older subjects with diabetes mellitus or hypertension (high blood pressure). We hypothesize that cocoa, which contains flavanols (a type of polyphenol), may help to promote blood flow to the brain in older people with diabetes or hypertension.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01
• Study First Submitted: 2009-01-20
• Study First Submitted QC: 2009-01-20
• Study First Posted: 2009-01-21
• Primary Completion: 2012-03
• Study Completion: 2013-06
• Status Verified: 2014-04
• Last Update Submitted: 2014-04-28
• Last Update Posted: 2014-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• diabetes and/or hypertension

Exclusion Criteria

• alzheimers disease, dementia, stroke, recent angina or heart attack

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
flavanol-rich cocoa	cocoa	-
flavanol-poor cocoa	cocoa	-

Primary Outcome Measures

Name	Time	Method
functional transcranial doppler measures	1 month

Trial Locations

Locations (1)

Brigham and Women's Hospital; 🇺🇸 Boston, Massachusetts, United States