NCT00825695已完成不适用
Flavanol-Rich Cocoa, Vascular Responses and Mechanisms
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- functional transcranial doppler measures
研究概览
简要总结
The purpose of the study is to learn whether or not cocoa has a beneficial effect on blood flow to the brain in older subjects with diabetes mellitus or hypertension (high blood pressure). We hypothesize that cocoa, which contains flavanols (a type of polyphenol), may help to promote blood flow to the brain in older people with diabetes or hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diabetes and/or hypertension
排除标准
- •alzheimers disease, dementia, stroke, recent angina or heart attack
研究组 & 干预措施
flavanol-poor cocoa
Placebo Comparator
干预措施: cocoa (Dietary Supplement)
flavanol-rich cocoa
Active Comparator
干预措施: cocoa (Dietary Supplement)
结局指标
主要结局
functional transcranial doppler measures
时间窗: 1 month
次要结局
未报告次要终点
研究者
Naomi DL Fisher, MD
Principal Investigator
Brigham and Women's Hospital
研究点 (1)
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