Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients With Non-segmental Vitiligo
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- Evaluation of Serum Interleukin-15 and Interleukin-22 Levels
研究概览
简要总结
Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients with Non-segmental Vitiligo before and after phototherapy
详细描述
This prospective study will include 30 patients with NSV, attending the Outpatient Clinics of Dermatology at Sohag University Hospitals, as well as 30 normal volunteers as control.
This study will be submitted for approval by Research and Ethical committees at Sohag Faculty of Medicine. An informed written consent will be obtained from each subject prior to participation in the study after full explanation of the procedure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •• Patients suffering from non segmental vitiligo.
- •Patients not on medical treatment or phototherapy for vitiligo in the last 3 months.
排除标准
- •• Patients with systemic or cutaneous inflammatory disorders.
- •Patients on treatment for vitiligo in last 3 months.
- •Pregnant and lactating patients.
- •Patients with history of diabetes.
- •Patients with history of autoimmune diseases.
结局指标
主要结局
Evaluation of Serum Interleukin-15 and Interleukin-22 Levels
时间窗: 3 months
3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate 1. Serum IL15 level . 2. Serum IL22 level. 3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate 1. Serum IL15 level . 2. Serum IL22 level.
次要结局
未报告次要终点
研究者
Samah Saeed Badrous
resident doctor at dermatology department balina central hospital
Sohag University