Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients With Non-segmental Vitiligo

Not Applicable

• Conditions: Vitiligo
• Interventions: Diagnostic Test: Interleukin-15 and Interleukin-22

• Registration Number: NCT05121532
• Lead Sponsor: Sohag University

Brief Summary

Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients with Non-segmental Vitiligo before and after phototherapy

Detailed Description

This prospective study will include 30 patients with NSV, attending the Outpatient Clinics of Dermatology at Sohag University Hospitals, as well as 30 normal volunteers as control.

This study will be submitted for approval by Research and Ethical committees at Sohag Faculty of Medicine. An informed written consent will be obtained from each subject prior to participation in the study after full explanation of the procedure.

Study Timeline

• Status Verified: 2021-11
• Study First Submitted: 2021-11-14
• Study First Submitted QC: 2021-11-14
• Last Update Submitted: 2021-11-14
• Study First Posted: 2021-11-16
• Last Update Posted: 2021-11-16
• Study Start: 2022-01
• Primary Completion: 2022-12
• Study Completion: 2022-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• • Patients suffering from non segmental vitiligo.

  • Patients not on medical treatment or phototherapy for vitiligo in the last 3 months.

Exclusion Criteria

• • Patients with systemic or cutaneous inflammatory disorders.

  • Patients on treatment for vitiligo in last 3 months.
  • Pregnant and lactating patients.
  • Patients with history of diabetes.
  • Patients with history of autoimmune diseases.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
non segmental vitiligo	Interleukin-15 and Interleukin-22	serum analysis
normal volunteer	Interleukin-15 and Interleukin-22	serum analysis

Primary Outcome Measures

Name	Time	Method
Evaluation of Serum Interleukin-15 and Interleukin-22 Levels	3 months	3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate; 1. Serum IL15 level .; 2. Serum IL22 level. 3 ml venous blood will be obtained from participante using commerciall available double antibody sandwich enzyme-linked immunosorbent assay (ELISA) kits to evaluate; 1. Serum IL15 level . 2. Serum IL22 level.