Effect of TAP Block on Ventilatory Function Following Abdominal Surgery

Phase 2

• Conditions: Laparotomy
• Interventions: Procedure: Regional analgesia infusion

• Registration Number: NCT01719796
• Lead Sponsor: Pierre and Marie Curie University

Brief Summary

Abdominal surgery impairs ventilation. Postoperative pain accounts for this impairment. Regional analgesia is known to reduce pain, thus to limit ventilatory impairment. The investigators hypothesized bilateral continuous transverse abdominal plan block would reduce ventilatory impairment following abdominal surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-10
• Study Start: 2012-10
• Study First Submitted: 2012-10-24
• Study First Submitted QC: 2012-10-30
• Last Update Submitted: 2012-10-30
• Study First Posted: 2012-11-01
• Last Update Posted: 2012-11-01
• Primary Completion: 2014-12
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• laparotomy

Exclusion Criteria

• below 18, pregnancy, prisoners

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Bilateral TAP catheter	Regional analgesia infusion	Ultrasonography guided bilateral TAP catheter insertion.

Primary Outcome Measures

Name	Time	Method
vital capacity	72h

Secondary Outcome Measures

Name	Time	Method
maximum forced expiratory flow	72h
analgesic consumption	72h
pain	72h	resting pain, assessed using VAS
diaphragmatic course	72h	using ultrasonography

Trial Locations

Locations (2)

Centre Hospitalier Universitaire de Saint-Etienne; 🇫🇷 Saint-Etienne, France

Centre Hospitalier Universitaire de Nîmes; 🇫🇷 Nîmes, France