Phacoemulsification Combined With Trabeculectomy Versus Phacoemulsification Combined With Trabeculotomy for Treatment of Chronic Angle Closure Glaucoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Absolute Success
研究概览
简要总结
A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.
详细描述
Patients were randomized into two groups: group A : patients will undergo two site phacoemulfication combined with trabeculectomy Group B with Phacoemulsification combined with ab-externo trabeculotomy. Preoperative assessments including full ophthalmic examination, anterior segment Optical Coherence Tomography (OCT) of the angle , endothelial cell count , visual fiend Perimetry and Biometry. Patients were followed up: first day, first week and every two months for 6 month. We will compare adverse effects and outcomes in both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with chronic angle closure glaucoma, with or without peripheral anterior synechiae, age more than 18
排除标准
- •Patient unable for follow up
- •Patients with corneal or retinal disease that affects visual outcome of surgery
- •Patients with previous glaucoma procedure in the eye of study
研究组 & 干预措施
Phacoemulsificaiton combined with ab-externo trabeculotomy
Patients will undergo two phacoemulsification combined with deep sclerectomy and ab-externo trabeculotomy
干预措施: Phacoemulsificaiton combined with ab-externo trabeculotomy (Procedure)
Phacoemulsification combined with trabeculectomy
Patients will undergo Two site phacoemulsification combined with trabeculectomy with Mitomycin C
干预措施: Phacoemulsification combined with trabeculectomy (Procedure)
结局指标
主要结局
Absolute Success
时间窗: 1,3,6 months
Reduction of IOP more than 30% on no glaucoma drops
Visual outcome
时间窗: 1,3,6 month
Uncorrected visual acuity by Snellen's chart
次要结局
- Adverse events(1 week, 1 month, 3 months, 6 months)
研究者
Mahmoud F. Rateb
Assitant Professor of Ophthalmology
Assiut University