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Influence of the Use of Hearing Protection in the Salivary Cortisol Level and in the Sleep of Premature Infants

Not Applicable
Conditions
Premature Newborn
Interventions
Device: use of earmuffs
Registration Number
NCT02781168
Lead Sponsor
Federal University of São Paulo
Brief Summary

The aim of this study was to investigate the influence of the use of headphones in salivary cortisol levels in newborns (NB) during periods of nap aimed at noise reduction, brightness and handling NB, measure the concentrations of salivary cortisol before (baseline) and after the use of hearing protection (response) in the neonatal intensive care unit (NICU).

A NICU nap periods and compare the influence of the use and non-use of hearing protection in salivary cortisol levels and sleep patterns of infants during nap periods of the NICU.

Detailed Description

The aim of this study was to investigate the influence of the use of headphones in salivary cortisol levels in newborns (NB) during periods of nap aimed at noise reduction, brightness and handling NB, measure the concentrations of salivary cortisol before (baseline) and after the use of hearing protection (response) in the NICU nap periods and compare the influence of the use and non-use of hearing protection in salivary cortisol levels and sleep patterns of infants during nap periods of the NICU. Being the chance prosposta the use of headphones during periods of environmental control has an influence on the level of salivary cortisol and sleep in preterm infants.

This is a randomized clinical trial, controlled, crossover, in which clinical intervention is introduced by the researcher that controls and varies, featuring experimental research.

In this study the intervention being tested is the use of hearing protection in infants. The ear is employed in certain periods of the day. These periods established by the Neonatal Intensive Care Unit (ICU), are intended to promote environmental noise control and manipulation of the NB.

Levels of cortisol present in the saliva of the newborn will be analyzed, allowing to measure the biologically active free cortisol in the body.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
12
Inclusion Criteria
  • Premature newborn male or female;
  • Inside the incubator;
  • Clinically stable;
  • No change in evoked otoacoustic emissions;
  • Current weight between 1200 to 2000g.
Exclusion Criteria
  • In phototherapy;
  • In invasive mechanical ventilation and noninvasive;
  • With any type of congenital malformation;
  • Periventricular hemorrhage with grade II, III and IV;
  • In using any medication depressant, analgesic or corticosteroid in last 24 hours;
  • Premature newborn whose mother has a history of illicit drug use during pregnancy.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
No use of earmuffsuse of earmuffsNo use of earmuffs are brand Natus® Pediatrics, Neonatal Noise Attenuators called MiniMuffs®, San Carlos, California, USA, which allow the reduction of sound pressure levels 7 to 12 decibels.
Use of earmuffsuse of earmuffsThe earmuffs are brand Natus® Pediatrics, Neonatal Noise Attenuators called MiniMuffs®, San Carlos, California, USA, which allow the reduction of sound pressure levels 7 to 12 decibels.
Primary Outcome Measures
NameTimeMethod
Comparison of Salivary Cortisol Levels and the Use of Hearing Protection19 months

The aim of this study was to investigate the influence of the use of earmuffs in salivary cortisol levels in newborns (NB) during periods of nap aimed at noise reduction.

Sleep of premature infants and use of earmuffs19 months

The aim of this study was to investigate the influence of the use of earmuffs in the sleep in premature infants.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hospital São Paulo

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São Paulo, Brazil

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