NL-OMON48367招募中4 期
Effect of citalopram on chest pain in patients with achalasia - CiPA
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 68
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Written informed consent
- •Minimum age: 18 years
- •Diagnosed with achalasia type 1 or 2
- •Previously treated with pneumodilatation, Heller*s myotomy or POEM
- •>=3 months post-treatment for achalasia
- •Recurrent chest pain
排除标准
- •Achalasia type 3 (**spastic type**)
- •Surgery of the esophagus (except Heller*s myotomy and POEM)
- •Currently using antidepressants
- •Chest pain suspect of cardiac origin.
- •Severe and clinically unstable concomitant disease (e.g. liver, cardiovascular or lung disease, neurological or psychiatric disorders, cancer or AIDS and other endocrine disorders)
- •Medication-related (contra-indications for citalopram)
研究者
相似试验
进行中（未招募）
1 期
Effect of citalopram on chest pain in patients with chest pain of unkown origiEUCTR2021-002288-24-NLAmsterdam UMC52
已完成
4 期
Effect of citalopram on chest pain in patients with functional chest pai'functional chest pain' and 'chest pain with unkown origin'10017977NL-OMON50787Academisch Medisch Centrum54
招募中
不适用
Effect of citalopram on chest pain in patients with achalasiaAchalasiaNL-OMON23216Amsterdam UMC (location AMC)48
进行中（未招募）
1 期
Effect of an antidepressant on chest pain in patients with achalasiaAchalasia is a motility disorder of the esophagus. Disappearance of myenteric neurons in the esophageal wall leads to failure of relaxation of the lower esophageal sphincter (LES) and impaired peristalsis. Symptoms of achalasia include dysphagia, regurgitation, chest pain and weight loss due to the stasis of food and liquids in the esophagus. Treatments effectively diminish the symptoms dysphagia and regurgitation, however have little effect on the occurrence of chest pain.EUCTR2019-001202-14-NLAmsterdam UMC68
终止
4 期
Effect of Citalopram on Chest Pain in Patients With Functional Chest PainFunctional Chest PainNCT05735756Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1