Dexmedetomodine versus midazolam for sedation inmechanically ventilated children: A randomized controltrial.

Not Applicable

• Conditions: Health Condition 1: null- critically ill children who are mechanically ventilated

• Registration Number: CTRI/2016/10/007347
• Lead Sponsor: AIIMS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 78

Inclusion Criteria

All mechanically ventilated children age 1 month to 15

years within 1 hour of intubation

Exclusion Criteria

1.Catecholamine resistant shock at time of

randomization (Shock persists despite use of the directacting

catecholamines i.e, epinephrine( >0.3 mcg/kg/min

or norepinephrine >0.3mcg/kg/min)

2.Children who are already receiving infusion of

sedation drugs(from the wards or referral hospital)

3.Severe bradycardia (HR < 60 beats/min)

4.AV-conduction block (I,II,III types)

5.Children with primary nervous system involvement

6. Hepatic impairment ((a)evidence of a known chronic

liver disease; (b)evidence of fulminant hepatic failure)

7. Need for muscle relaxation at the time of

randomization(may only be used for intubation and

initial stabilization)

8. Previous participation in this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified