Cost Effectiveness of Two Different Implementation Procedures to Change Clinicians Practice Roles in the Detection of Hereditary Colorectal Cancer
试验速览
- 阶段
- 不适用
- 入组人数
- 360
- 试验地点
- 14
- 主要终点
- Efficacy of inclusion of eligible CRC-patients for MSI testing by pathologists.
研究概览
简要总结
The purpose of this study is to compare two different strategies to implement a new method to identify patients with HNPCC, which appeared cost-effective and feasible. The effectiveness, costs and feasibility of both of the implementation strategies will be assessed.
详细描述
The Radboud University Nijmegen Medical Centre developed a new method to identify patients with HNPCC. This method appeared cost-effective and feasible. Using this new method 70% of the HNPCC patients will be identified as compared to less than 30% when the current method is used. However, this new method does not implement itself; large gaps exists between best evidence and daily practice. This study will compare an intensive strategy, consisting of distribution of educational materials, education, feedback and reminders, with a minimal strategy, only consisting of distribution of a critical care pathway. The aim is to find the most cost-effective strategy to implement the new method to identify patients with HNPCC in the Netherlands.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Single
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Colorectal cancer before the age of 50 years
- •Second colorectal cancer at any age
- •Colorectal cancer and other HNPCC associated extracolonic cancer irrespective of age at diagnosis
- •Adenoma with high grade dysplasia diagnosed before the age of 40 years
排除标准
- 未提供
结局指标
主要结局
Efficacy of inclusion of eligible CRC-patients for MSI testing by pathologists.
Efficacy of referral of patients who are MSI positive to a clinical geneticist by surgeons.
次要结局
- Experiences with and acceptance of changed physician practice roles by patients and clinicians.
- Cost efficacy of the implementation procedures.