The effect of Curcumin on LP(a) and hs-CRP in diabetes patients and concurrent coronary artery diseases( coronary artery disease less than 50% obstruction)
- Conditions
- CAD.Chronic ischaemic heart disease
- Registration Number
- IRCT20130811014330N4
- Lead Sponsor
- Mashhad University of Medical Sciences,vice chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 64
Patients with coronary artery disease which were selected by cardiologist
Male/ Female older than 18 years
diabetic patients
Coronary artery stenosis in angiography less than 50%
Pregnant and breast-feeding patients;
Rheumatic disease;
Chronic liver diseases;
Renal diseases;
Every types of malignancies;
Infectious diseases in the last 3 months;
Patients with any surgical procedures in the preceding 3 months;
Subjects who had a history of angioplasty or coronary by-pass graft surgery;
major trauma or an immunologic disease;
Subjects who were using steroids, penicillin, oral contraceptive or hormone replacement therapy;
Inflammatory bowel disease, psoriasis, multiple sclerosis, systemic lupus erythematosus, myasthenia gravis, autoimmune thyroiditis.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of lipoprotein (a). Timepoint: at the baseline and 3 months after intervention. Method of measurement: ELISA.;Serum level of hs-CRP. Timepoint: at the baseline and 3 months after intervention. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method HbA1C. Timepoint: Before intervention and 3 months after intervention. Method of measurement: autoanalyzer bt3000.;Fast blood sugar (FBS). Timepoint: Before intervention and 3 months after intervention. Method of measurement: autoanalyzer bt3000.