Syntethic vs. natural estrogen in combined oral contraception- effect on insulinsensitivity, inflammation, coagulation and endometrium. A comparison with a progestin-only preparatio

• Conditions: Healthy women, contraception; MedDRA version: 17.0Level: LLTClassification code 10073728Term: Hormonal contraceptionSystem Organ Class: 100000004865; Therapeutic area: Body processes [G] - Reproductive physiologi cal processes [G08]

• Registration Number: EUCTR2014-001243-20-FI
• Lead Sponsor: Helsinki University Central Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-05-20
• Last Update Posted: 16 June 2014

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

woman aged 18-35, normal weight BMI 19-24.9 kg/m2, good general health: no diagnosed disease or regular medications, regular mentrual cycle (21-35 days), prior to entering the study min. 2 months wihout hormonal contraception, no contraindications for the use of hormonal oral combined contraception
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 60
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

abnormal results in 2h oral glucose tolerance test, abnormal findings in gyneacological exam (inc. sonography), blood pressure >140/90 mmHg, regular (daily) smoking, alcohol or drug abuse

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified