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Clinical Trials/NCT02246946
NCT02246946
Completed
Not Applicable

Efficacy of the Addition of Positive Airway Pressure to Conventional Chest Physiotherapy in the Time to Resolution of Pleural Effusion After Drainage

Universidade Cidade de Sao Paulo1 site in 1 country156 target enrollmentDecember 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pleural Effusion
Sponsor
Universidade Cidade de Sao Paulo
Enrollment
156
Locations
1
Primary Endpoint
Duration of chest tube drainage
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this study is to determine if the addition of intermittent positive airway pressure breathing (specific lung expansion technique) to conventional chest physiotherapy chest drainage is effective to accelerate the reabsorption of pleural effusion and consequently decrease the duration of chest tube drainage and respiratory system impairment. These effects would decrease hospital stay lengths and the incidence of pulmonary complications.

Registry
clinicaltrials.gov
Start Date
December 2014
End Date
December 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Universidade Cidade de Sao Paulo
Responsible Party
Principal Investigator
Principal Investigator

Adriana Claudia Lunardi

Professor on Master's and Doctoral Programs in Physical Therapy of Universidade Cidade de São Paulo

Universidade Cidade de Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • age over 18 years
  • presence of pleural effusion
  • have undergone chest drain for fewer than 24 hours

Exclusion Criteria

  • contraindication to the use of non-invasive equipment that generates positive airway pressure (such as: intolerance, phobia, drowsiness, restlessness, confusion, hemodynamic instability requiring vasopressor therapy, systolic blood pressure \< 90 mmHg, facial trauma, ineffective cough or inability to swallow, nausea or vomiting, upper gastrointestinal bleeding, acute myocardial infarction within the last 48 hours, pneumothorax or bullous emphysema)

Outcomes

Primary Outcomes

Duration of chest tube drainage

Time Frame: All patients will be followed for the duration of hospital stay, an expected average of 7 days of chest drainage

The criteria for the removal the chest drain will an output of transudative fluid over 24h ≤ 200 ml and full lung expansion on chest radiography

Secondary Outcomes

  • Length of hospital stay(All patients will be followed for the duration of hospital stay, an expected average of 10 days)
  • Spirometry(On the 4th and 8th days after the beginning of the intervention protocol. Or on the day of hospital discharge if it occurs prior to the 8th day of protocol)
  • Pulmonary complications(All patients will be followed for the duration of hospital stay, an expected average of 10 days)
  • Peripheral Oxygen Saturation(On the 4th and 8th days after the beginning of the intervention protocol. Or on the day of hospital discharge if it occurs prior to the 8th day of protocol)

Study Sites (1)

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