跳至主要内容
临床试验/CTRI/2024/09/074041
CTRI/2024/09/074041尚未招募不适用

Supine percutaneous nephrolithotomy (PCNL) in renal stone patients

Gandhi medical college1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年9月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To conclude the overall feasibility of supine PCNL.

研究概览

简要总结

Percutaneous nephrolithotomy (PCNL) is considered the best treatment option for large and complex renal stones, which are difficult to manage by using other treatment modalities like ureteroscopy and shock wave lithotripsy (SWL) and retrograde intra renal surgery (RIRS). This minimally invasive surgical intervention has a high stone clearance rate with low morbidity. Traditionally PCNL is being done in prone position but it has evolved many a fold and was originally described in supine position by Valdivia et al. In this position the direction of the tract is posterior and thus preserves a low pressure in the renal pelvis, and thereby reduces the risk of fluid absorption and allows spontaneous clearance of fragments by gravity directed flow of fluid. Later on some new positions were described after doing some modification in the original Valdivia. Currently, PCNL is the treatment of choice for large renal stones, staghorn calculi, or in stones occurring in kidneys with abnormal anatomy. The morbidity of the PCNL in prone position been well documented. However, the supine approach’s safety and efficacy and potential advantages likely explain the increasing use of the supine position for stone management over the last ten years .  Nevertheless, despite previously reported advantages, it has been pointed out that the supine position has its flaws, such as prolonged operative time in the case of larger stones. At present, current guidelines do not support one approach over the other. Therefore, controversy still exists regarding which position is safer and more effective for PCNL.  In this study we aim to investigate the feasibility and outcome of the supine PCNL position by analyzing preoperative, intraoperative and post operative data and conclude outcomes of this position.

研究设计

研究类型
Observational

入排标准

年龄范围
15.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • All patients of renal stones requiring PCNL according to standard guidelines.

排除标准

  • Patients with coagulopathy Patients with abnormal anatomy of collecting system.
  • Patient not fit for surgery and not willing to give consent.

结局指标

主要结局

To conclude the overall feasibility of supine PCNL.

时间窗: 1 year 6 months

次要结局

  • To assess complications associated with supine PCNL. To compare the outcome with the available data.(1 year 6 months)

研究者

发起方
Gandhi medical college
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Saurabh kumar

Gandhi medical college

研究点 (1)

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