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The effect of cortical motor center phrenic nerve circuit regulated by nerve on pulmonary rehabilitation of COPD

Phase 1
Conditions
COPD
Registration Number
ITMCTR2200006800
Lead Sponsor
Shaanxi Traditional Chinese Medicine Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

? Aged 18-80 (including 18 and 80);
? Patients with severe chronic obstructive pulmonary disease (COPD) in group C meeting the diagnostic criteria;
? There is no acute exacerbation within 4 weeks (the patient is in the stable period, or the inpatients in the acute exacerbation period enter the stable period after standardized treatment);
? Sign the informed consent;

Exclusion Criteria

? COPD patients with asthma, pulmonary tuberculosis, bronchiectasis, lung cancer and other patients who are not suitable for pulmonary rehabilitation;
? COPD patients with serious cardiovascular, cerebrovascular, liver, kidney, blood, endocrine and other major diseases;
? Patients with severe musculoskeletal diseases;
? There are metal foreign bodies within 30cm of the treatment site;
? Long term oxygen inhalation is required. Spontaneous pneumothorax or recurrent pneumothorax, giant pulmonary bullae and rib fracture have occurred in the past six months;
? High spinal cord injury, muscle disease;
? No drugs that affect nerve conduction and muscle contraction, such as vecuronium bromide, benzodiazepines and aminoglycosides, were used within one week.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pulmonary function;Phrenic motor evoked potential;Blood gas analysis;
Secondary Outcome Measures
NameTimeMethod
6-minute walk distance measurement;MCSS score;CAT score;MMRC score;
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