Drinking water under a One Health lens: quantifying microbial contamination pathways between livestock and drinking water

Not Applicable

Completed

• Conditions: Self-reported diarrhoeal disease; Digestive System; Diarrhoeal disease

• Registration Number: ISRCTN69058168
• Lead Sponsor: niversity of Southampton

Brief Summary

2020 results in https://doi.org/10.1016/j.ijheh.2020.113602 (added 23/04/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-19
• Study Completion: 2018-12-14
• Last Update Posted: 3 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 234

Inclusion Criteria

1. Children aged 6-59 months (as the cohort at greatest risk of diarrhoeal disease) in households
2. Participating in an ongoing population-based animal syndromic surveillance (PBASS) study

Exclusion Criteria

Child's carer/parent unavailable or unable to provide informed consent

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
E. coli and intestinal enterococci in household stored water are measured respectively through membrane filtration (0.45µm pore size) and culture with chromogenic coliform agar medium (incubation period: 24 hours) and m-Enterococcus agar medium (incubation period: 48 hours), followed by enumeration of both target organisms at baseline and 12 weeks thereafter.

Secondary Outcome Measures

Name	Time	Method
Self-reported diarrhea (defined as =3 loose stools within a 24-hour period) is measured using questionnaire interview to household members at 1 week and 13 weeks.