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Clinical Trials/NCT05763810
NCT05763810
Active, not recruiting
Not Applicable

Analgesic Effects of Erector Spinae Plane Block Versus Superficial Parasternal Intercostal Plane Block Combined With Rectus Sheath Block After Off Pump Cardiac Surgery: A Randomised Trial

Abd-Elazeem Abd-Elhameed Elbakry1 site in 1 country22 target enrollmentMarch 15, 2023
ConditionsAnalgesia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Analgesia
Sponsor
Abd-Elazeem Abd-Elhameed Elbakry
Enrollment
22
Locations
1
Primary Endpoint
Total opioid consumption
Status
Active, not recruiting
Last Updated
12 months ago

Overview

Brief Summary

This study aims to compare the analgesic effects of erector spinae plane block versus Superficial Parasternal Intercostal Plane Block block along with rectus sheath block after off-pump cardiac surgery

Detailed Description

General anaesthesia will be used for all patients. induction by midazolam 0.05-0.1 mg/kg, fentanyl 2-5 µ/kg, propofol 1-2 mg/kg, and atracurium 0.5 mg/kg for intubation. Maintenance by sevoflurane in oxygen-air mixture. regional blocks will be used after the induction of anaesthesia. Intraoperative analgesia will be maintained by fentanyl infusion 1-2 µ/kg/h while morphine sulphate 2.5-5mg will be used as rescue analgesia when pain score\>4 beside acetaminophen 1000 mg /6 hours

Registry
clinicaltrials.gov
Start Date
March 15, 2023
End Date
December 2025
Last Updated
12 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Abd-Elazeem Abd-Elhameed Elbakry
Responsible Party
Sponsor Investigator
Principal Investigator

Abd-Elazeem Abd-Elhameed Elbakry

Assistant professor

Menoufia University

Eligibility Criteria

Inclusion Criteria

  • American Society of anaesthesiologists physical status classification II-III
  • Elective off-pump cardiac surgery

Exclusion Criteria

  • Cognitive impairment
  • Allergy to local anaesthetics
  • Renal and/or hepatic dysfunction
  • Ejection fraction\< 45%

Outcomes

Primary Outcomes

Total opioid consumption

Time Frame: Perioperative.

µg and mg

Secondary Outcomes

  • Duration of hospital stay(Postoperative up to 4 weeks)
  • Postoperative vomiting(Perioperative)
  • Extubation time(Perioperative)
  • Pain intensity at rest and exercise(Perioperative.)
  • Duration of post anaesthesia care unit stay(Perioperative)
  • Postoperative nausea(Perioperative)

Study Sites (1)

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