Irrisept in Emergency General Surgery Patients
Not Applicable
- Conditions
- Emergency SurgerySurgical Site Infections
- Interventions
- Drug: Normal Saline
- Registration Number
- NCT07048899
- Brief Summary
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- All patients (>18 years old at time of enrollment) who are hospitalized at UT Tyler and undergo an open (or conversion to open) wound class 2-4 surgical procedure for an emergent surgical condition.
Exclusion Criteria
- Those <18 years of age
- Pressure wounds
- Superficial abscesses (as primary diagnosis)
- intra-abdominal abscess due to previous technical failure
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Standard of Care (Normal Saline) Normal Saline Irrigation with Normal Saline Intervention (Irrisept) Chlorhexidine Irrigation with Irrisept
- Primary Outcome Measures
Name Time Method Surgical Site Infection Rate Time of enrollment to 30 days Determine if the rate of SSI is different
- Secondary Outcome Measures
Name Time Method Length of Stay From date of admission until date of discharge from the hospital, assessed up to 30 days post-operatively Number of days admitted to hospital
Incidence of SSI and surgical wound class with the use of Irrisept Time of enrollment to 30 days Correlation between surgical wound class and the use of Irrisept on the incidence of SSI
Readmission Rates due to SSI From day of surgery to 30 days How often a patient has to be re-admitted to the hospital for a surgical site infection
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does Irrisept utilize to reduce surgical site infections in emergency general surgery?
How does the efficacy of Irrisept irrigation compare to standard-of-care normal saline in preventing SSIs in emergency surgical cases?
Are there specific biomarkers that can predict patient response to Irrisept irrigation in the context of emergency general surgery?
What are the known or potential adverse events associated with the use of Irrisept in surgical settings and how are they managed?
What related compounds or combination therapies are being explored alongside antiseptic irrigation solutions like Irrisept for SSI prevention in emergency surgery?
Trial Locations
- Locations (1)
UT Health Tyler
🇺🇸Tyler, Texas, United States
UT Health Tyler🇺🇸Tyler, Texas, United States