Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder

Not Applicable

Completed

• Conditions: Borderline Personality Disorder; Sleep Disturbances; Depression
• Interventions: Other: light therapy

• Registration Number: NCT01311193
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment.

Treated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-03
• Study First Submitted: 2011-03-03
• Study First Submitted QC: 2011-03-07
• Last Update Submitted: 2011-03-07
• Study First Posted: 2011-03-09
• Last Update Posted: 2011-03-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• Borderline Personality Disorder (DSM IV-criteria)
• German-speaking
• normal ocular function

Exclusion Criteria

• lack of compliance

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
light therapy	light therapy	Morning bright light treatment (at 8000 lux for 40min, daily during 3 weeks)

Trial Locations

Locations (1)

Centre for Chronobiology, Psychiatric Hospital, University of Basel; 🇨🇭 Basel, BS, Switzerland