Relationship and differences between Central Aortic and Peripheral Blood Pressure measurement performed with same device
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,200
- 试验地点
- 7
- 主要终点
- To establish correlation and differences between brachial blood pressure and central blood pressure so as to establish the cut-off values (threshold values) for central blood pressure based on the brachial blood pressure.
研究概览
简要总结
Accumulatingevidence indicates that central blood pressure (CBP) is a better cardiovascularrisk predictor than brachial blood pressure (BBP). Although more additionalbenefits of CBP based treatment above usual hypertension treatment are to bedemonstrated, the demand for implementing CBP assessment in general clinicalpractice is increasing. For this, the measurement procedure must be non-invasive,easy to perform, and cost- and time-efficient. Therefore, oscillometric deviceswith the possibility to assess CBP seem the best option
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •Outpatients with hypertension (BP greater than 140/90 mm Hg or any level of blood pressure in persons on antihypertensive medications)
- •Newly Diagnosed Hypertensive Patients
- •Normotensive patients on antihypertensive
- •Hypertensive subjects with a family history of premature coronary heart disease
- •Hypertensive patients with comorbidities (Diabetes, Dyslipidaemia, CAD, left ventricular hypertrophy, peripheral arterial disease, cerebrovascular disease, microalbuminuria or proteinuria).
排除标准
- •Subjects with evidence of recent event (MI < 1-month duration, treated angina at the time of enrolment, a cerebrovascular event in the 3 months before enrolment, heart failure, uncontrolled arrhythmias, or any clinically important haematological or biochemical abnormality on routine screening)
- •In-patients/Hospitalized patients
- •Pregnant Women.
结局指标
主要结局
To establish correlation and differences between brachial blood pressure and central blood pressure so as to establish the cut-off values (threshold values) for central blood pressure based on the brachial blood pressure.
时间窗: 1 Year
次要结局
- To establish the correlation between CBP and BBP with organ damage (LV hypertrophy, End-stage kidney disease etc)(1 Year)