The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

Completed

• Conditions: Stable Angina Pectoris; Correlation Analysis; Diagnostic Value; Acupoint Sensitization

• Registration Number: NCT03341663
• Lead Sponsor: West China Hospital

Brief Summary

Investigators adopt cross-sectional study design to carry out the exemplary research in the aspects of disease diagnosis.This study is designed to confirm the hypothesis "acupoint sensitization is associated with a severity of angina pectoris, which may contribute to the diagnosis of stable angina pectoris". After the eligible participants recruited in group, the coronary artery lesions will be evaluated through coronary angiography and the Canadian Cardiovascular Society(CCS) angina pectoris classification will also be evaluated at the same time. The degree of acupoint sensitization will be tested by the electronic Von Frey instrument by one professional acupuncturist with total 12 acupoints, including Shenmen,Yinxi, Shaohao,Jiquan,Neiguan, Ximen, Quze, Shanzhong, Juque, Jueyinyu, Xinyu, Duyu. Analysis were conducted to explore relationships between the degree of acupoint sensitization, the degree of coronary artery stenosis and CCS angina pectoris classification. Diagnostic value will be further analyzed in the final step.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-26
• Study First Submitted QC: 2017-11-13
• Study First Posted: 2017-11-14
• Study Start: 2017-12-06
• Primary Completion: 2018-10-28
• Study Completion: 2018-11-29
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 183

Inclusion Criteria

• Patients meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease
• The frequency of angina attacks were greater or equal to twice a week over the previous 3 months
• Patients agree to do coronary angiography examination and sign the informed consent.

Exclusion Criteria

• People with mental disabilities and intelligent obstacle
• Patients who can't accomplish the detection of acupoint sensitization
• Patients with allergic condition, especially the contrast media
• Patients with acute myocardial infarction, unstable angina, during arrhythmia and serious diseases which can affect the blood supply of myocardial
• Patients with skin or peripheral nerve paresthesia, pain or the detect area of skin ulcerate
• Pregnant or lactating women
• Patients who undergoing other clinical trials

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The degree of acupoint sensitization	About 1 hour	The value will be obtained through the electronic Von Frey instrument
The degree of coronary artery stenosis	About 2 hours	Data will be obtained through coronary angiography
Canadian Cardiovascular Society angina pectoris classification	About 1 hours

Trial Locations

Locations (1)

The West China Hospital of Sichuan university; 🇨🇳 Chengdu, Sichuan, China