Quality of Life in Patients With Multiple Myeloma-validation Study

Terminated

• Conditions: Multiple Myeloma
• Interventions: Diagnostic Test: Myeloma Patient Outcome Scale (MyPOS)

• Registration Number: NCT03537222
• Lead Sponsor: Zurich University of Applied Sciences

Brief Summary

In this study, the Myeloma Patient Outcome Scale (MyPOS) will be translated from English to German. This translated version will be quantitatively and qualitatively validated with patients with multiple myeloma.

Detailed Description

Patients with multiple myeloma (N=10) will be interviewed in the qualitative phase about their comprehension of the translated MyPOS. The questionnaire will be revised according to the results of the interviews. This culturally adapted Swiss-German MyPOS will be assessed in the quantitative phase for its' psychometric properties with 200 patients with multiple myeloma.

Study Timeline

• Study First Submitted: 2018-05-15
• Study First Submitted QC: 2018-05-15
• Study First Posted: 2018-05-25
• Study Start: 2018-10-10
• Primary Completion: 2021-07-31
• Study Completion: 2021-07-31
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-05
• Last Update Posted: 2021-10-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• informed consent as documented by signature
• confirmed histological diagnosis of multiple myeloma,
• age ≥ 18 years,
• mental capacity to give written informed consent

Exclusion Criteria

• inability to communicate in German
• participation in another clinical study
• more than one cancer diagnosis
• mental illness (i.e. psychiatric diagnosis)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
MyPOS	Myeloma Patient Outcome Scale (MyPOS)	-

Primary Outcome Measures

Name	Time	Method
Psychometric properties of the culturally-adapted Swiss-German Myeloma Patient Outcome Scale (MyPOS)	upon enrollment	The primary outcome will be the scores on each item of the culturally-adapted Swiss-German MyPOS. Items are scored on a five-point Likert scale. For the analysis, the three subscales "Symptoms" (range: 0-52), "Emotions" (range:0-68) and "Healthcare Support" (range: 0-12) are assessed as well as the MyPOS total score (range: 0-132 ) by summing up the item scores ranging from 0-4. Higher scores reflect worse quality of life.; The scores will be used to evaluate the psychometric properties of the culturally-adapted Swiss-German MyPOS: * Structural validity,; * Internal consistency,; * Construct validity,; * Convergent and divergent validity.

Trial Locations

Locations (3)

Kantonsspital Münsterlingen; 🇨🇭 Münsterlingen, Thurgau, Switzerland

Kantonsspital Aarau; 🇨🇭 Aarau, Zurich, Switzerland

Onkozentrum Hirslanden; 🇨🇭 Zurich, Switzerland