Validation of Diagnostic Performance of Ultrasound Elastography for Detection of Thyroid Cancer
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 590
- Locations
- 1
- Primary Endpoint
- Diagnostic performance of elastography using in-vivo compression for detection of thyroid cancer
Study Overview
Brief Summary
For patients with thyroid gland nodule, fine-needle aspiration biopsy has been proved to be an efficient tool for thyroid cancer diagnosis. However, it is somewhat an invasive procedure and is subject to sampling and analysis uncertainties. Thus, improved, more reliable criteria for determining which nodule should be be aspirated are needed. Ultrasound elastography has been shown to be useful in the differential diagnosis of breast and prostate cancers. Ultrasound elastography also may discriminate malignant from benign nodule.
Detailed Description
To prospectively evaluate the elastographic appearance of thyroid cancer and explore the potential sensitivity and specificity of elastography for differentiating benign and malignant tumors, with histopathologic analysis as the reference standard.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •The patients with thyroid nodule who are supposed to take fine needle aspiration biopsy
Exclusion Criteria
- •The patients who do not want to participate in the study
Outcomes
Primary Outcomes
Diagnostic performance of elastography using in-vivo compression for detection of thyroid cancer
Time Frame: 1 year
Measuring ECI(Elasticity contrast index) of thyroid nodule by ultrasound elastography
Secondary Outcomes
- Determination of the parameters which could have influence on the diagnostic performance of ultrasound elastography using in-vivo compression(One year)
Investigators
Dong Jun Lim
SeoulStMary
Seoul St. Mary's Hospital