Diagnostic Performance of Ultrasound Elastography for Detection of Thyroid Cancer
- Conditions
- ElastographyThyroid Nodule
- Registration Number
- NCT02462512
- Lead Sponsor
- Dong Jun Lim
- Brief Summary
For patients with thyroid gland nodule, fine-needle aspiration biopsy has been proved to be an efficient tool for thyroid cancer diagnosis. However, it is somewhat an invasive procedure and is subject to sampling and analysis uncertainties. Thus, improved, more reliable criteria for determining which nodule should be be aspirated are needed. Ultrasound elastography has been shown to be useful in the differential diagnosis of breast and prostate cancers. Ultrasound elastography also may discriminate malignant from benign nodule.
- Detailed Description
To prospectively evaluate the elastographic appearance of thyroid cancer and explore the potential sensitivity and specificity of elastography for differentiating benign and malignant tumors, with histopathologic analysis as the reference standard.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 590
- The patients with thyroid nodule who are supposed to take fine needle aspiration biopsy
- The patients who do not want to participate in the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diagnostic performance of elastography using in-vivo compression for detection of thyroid cancer 1 year Measuring ECI(Elasticity contrast index) of thyroid nodule by ultrasound elastography
- Secondary Outcome Measures
Name Time Method Determination of the parameters which could have influence on the diagnostic performance of ultrasound elastography using in-vivo compression One year Analysis of clinical characteristics of thyroid nodules and patients which are related to the diagnostic performance of ultrasound elastography
Trial Locations
- Locations (1)
Seoul St Mary's Hospital
🇰🇷Seocho-gu, Seoul, Korea, Republic of