The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory in Stroke, Parkinson, and Elderly Patients
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Central Nervous System Diseases
- Sponsor
- Taipei Veterans General Hospital, Taiwan
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Change of Repeatable Battery for the Assessment of Neuropsychological Status
- Last Updated
- 5 years ago
Overview
Brief Summary
The investigators hypothesize that ten sessions of repetitive transcranial magnetic stimulation yield ability to upregulate the function of primary motor cortex and prefrontal cortex that play key roles in motor and frontal memory processing.
Detailed Description
Excitatory (\>3Hz) rTMS could facilitate the brain cortex and neuroplasticity that benefits motor control and working memory when the coil is applied over primary motor cortex or dorsolateral prefrontal gyrus.
Investigators
vghtpe user
Principal investigator
Taipei Veterans General Hospital, Taiwan
Eligibility Criteria
Inclusion Criteria
- •Ischemic or hemorrhagic cerebrovascular lesion,
- •Parkinson's disease
Exclusion Criteria
- •With metal implantation
- •Dementia or severe cognitive impairment
Outcomes
Primary Outcomes
Change of Repeatable Battery for the Assessment of Neuropsychological Status
Time Frame: Up to 12 weeks
Test cognition including memory, attention, language...
Secondary Outcomes
- Change of Montreal Cognitive Assessment(Up to 12 weeks)
- Change of Fugl-Meyer Assessment , Wolf Motor Function Test(Up to 12 weeks)