Combined oral and topical antimicrobial therapy for male partners of women with bacterial vaginosis: acceptability, tolerability and impact on the genital microbiota of couples - stage 2

Monash University0 个研究点目标入组 89 人开始时间: 2018年2月9日最近更新: 2020年4月14日

适应症

试验速览

暂无简介。

•Women will be eligible if they:
•1. are 18-55 years of age
•2. have symptomatic BV, microbiologically defined as a Nugent score of 4-10 and 3-4 Amsel criteria,
•3. are willing and able to comply with protocol requirements
•4. have a regular male partner who is willing to be enrolled in the trial
•5. must have been in a relationship with their regular male partner for at least two months at the time of enrolment
•Men will be eligible if:
•1. their regular female partner meets the eligibility criteria
•2. they are willing and able to comply with protocol requirements, which includes enrolling within a week of their partner

•Women will be ineligible if they:
•1. are HIV positive
•2. are pregnant or breast feeding
•3. are diagnosed with current PID
•4. have an allergy to both first line antibiotics for BV, metronidazole and clindamycin
•5. test positive for C.trachomatis, N.gonorrhoeae or T.vaginalis at baseline
•6. have other current sexual partners
•7. are a current sex worker
•Men will be ineligible if they:
•1. report a drug allergy to metronidazole or clindamycin,
•2. are HIV positive
•3. have other current sexual partners
•4. are a current sex worker

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