Comparative study between continuous perfusion and split doses in the treatment of postoperative pain - Elastomeric pumps versus intravenous split doses in postoperative pain

Hospital Universitari Sagrat cor0 个研究点开始时间: 2015年12月10日最近更新: 2017年5月22日

适应症

试验速览

暂无简介。

•- Over 18 years old
•- Patients with analgesic needs superior to 48 hours and an equivalent minimal in-hospital stay.
•- Patients undergoing:
•. Orthopaedic Surgery: hip prosthesis, shoulder pathologies
•. General Surgery: eventroplasty, anal fissure and cholectomy
•. Gynecologic Surgery: hysterectomy
•- Patients providing informed consent
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 100
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 84

•- Non elective surgery
•- Different analgesic requirements
•- Patient admission to ICU
•- Allergy or hypersensitivity to any drug used in the study
•- Contraindication for any of the study drugs:
•. Medical history of agranulocytosis and aplastic anemia
•. Acute intermittent porphyria
•. Glucose 6 phosphate dehydrogenase deficiency
•. Digestive haemorrhage, esophageal haemorrhage, active peptic ulcer, cranial haemorrhage.
•. Respiratory depression
•. Severe chronic obstructive pulmonary disease
•- Pregnancy suspicion
•- Failure or severe hepatic insufficiency: score: Child-Pugh 10-15
•- Failure or mild-severe renal insufficiency: CICr <50ml/min or creatinine >2mg/dl
•- Severe emotional depression, dementia and/or mental disorders
•- Obesity: Body mass index >30 Kg/m2
•- Refusing to provide informed consent

发起方

Hospital Universitari Sagrat cor