Effect of high flow oxygen therapy on respiratory function following upper abdominal surgery
- Conditions
- Health Condition 1: Y839- Surgical procedure, unspecified asthe cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
- Registration Number
- CTRI/2020/12/029680
- Lead Sponsor
- Vimi Rewari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1)ASA grade 1 and 2 patients.
2)Able to understand verbal instructions and provide informed consent.
3)Undergoing elective upper abdominal surgery , involving an abdominal incision longer than 5 cm that is above or extending above the umbilicus.
1) Patient refusal to participate in the study
2) Patients undergoing emergency laparotomy
3) Patients with tracheostomy, pleural effusion, pneumothorax, pulmonary atelectasis, k/c/o COPD/Restrictive lung disease
4) Intra operative massive blood loss( >40 ml/kg)/ massive transfusion( >8 PRBC during Surgery)
5) Known deformity of chest wall or thoracic spine .
6) Patients with history of previous thoracic surgery
7) BMI >30 kilograms per meter square.
8)Obstructive Sleep apnea
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect of HFNO2 on inspiratory diaphragmatic excursion after upper abdominal surgeryTimepoint: Preoperatively, 2 hours after extubation and 24 hours after extubation
- Secondary Outcome Measures
Name Time Method 1)To evaluate the effect of HFNO2 on lung aeration as assessed by Lung Ultrasound Score <br/ ><br>2)To evaluate the effect of HFNO2 on post operative oxygenation as assessed by PaO2/FiO2 ratio <br/ ><br>3) To determine the clinical variables associated with post operative diaphragmatic dysfunction and loss of lung aeration. <br/ ><br>4)To determine the correlation of diaphragmatic dysfunction with <br/ ><br>- Lung ultrasound scores <br/ ><br>- PaO2/FiO2 ratio <br/ ><br>- Body mass index <br/ ><br>- Age <br/ ><br>- Duration of surgeryTimepoint: Preoperatively, 2 hours after extubation and 24 hours after extubation