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临床试验/NCT02363088
NCT02363088已完成不适用

Can Text Reminders Improve Uptake of Cervical Screening? A RCT.

Sarah Huf1 个研究点 分布在 1 个国家目标入组 14,597 人开始时间: 2015年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
14,597
试验地点
1
主要终点
Intention to treat analysis

研究概览

简要总结

Cervical cancer is the most common cancer in women under 35 years and is a major public health concern. Fortunately, the natural history of this malignancy can be beneficially improved through cytological screening. However, the success of screening programmes depends on their ability to attract the "at risk" population, as well as the analytical sensitivity and specificity of the screening test. In the UK, screening consistently falls short of the 80% national target and recent evidence shows uptake is decreasing, in part due to the introduction of HPV vaccination programmes. In the under 30s London population, average coverage only reached 50% in 2013. Given this information, the cervical screening programme is under increasing pressure to improve uptake, and need an evidence based intervention.

We aim to improve the uptake of cervical screening using SMS messaging through a randomised controlled trial. The trail will evaluate both the prevalent and incident rounds of screening and within the intervention group, analyse how the content of text reminders influences their effectiveness. Specifically we will evaluate a) neutral b) messenger c) social norms d) framed gain/loss reminders. Unlike our previous trial, this SMS reminder will encourage the booking of an appointment which has never been tested, rather than simply reminding women to attend. All women being invited for cervical screening, registered at participating GPs within Hillingdon will be eligible to participate. Women will also be provided with a 2 week window during which they can opt out of the research. Given the sample sizes we predict the trial will take 9 months.

详细描述

In Hillingdon specifically, where this randomised controlled trial (RCT) will be set, the uptake of the prevalent population of women (24-29 years as a proxy), was only 35% in 2012, whilst the incident population (30-64years as a proxy) was slightly higher at 51% (HSCIC2, 2013).

One strategy which healthcare has previously employed to improve uptake of both screening and routine appointments is the use of SMS or "text message" reminders. Standard reminders have often been used in healthcare and act as "primers", prompting people to make healthier choices (Blumenthal-Barby & Burroughs, 2012). They also serve to reduce the practical barriers preventing women from attending i.e. failure to book or remember the time/location of the appointment. Previous research investigating the effectiveness of appointment reminders demonstrated that both telephone and postal reminders, although at times effective, were often impractical, unsustainable, and/or unaffordable (Gurol-Urganci et al, 2013, Perron et al, 2013).

SMS interventions have been effective at improving medication adherence, disease management and smoking cessation (Krishna et al, 2013; Abroms et al, 2014). They have also proven effective at reducing "Do Not Attends" (DNAs) within healthcare, estimated to cost the NHS £600 million per year in wasted time and resources (Dr Foster Research, 2009). SMS reminders were also found to be very successful at increasing the attendance of breast screening appointments, increasing the uptake by 17% compared to usual care (Kerrison et al, 2013). As well as improving attendance, SMS reminders have also proved effective at reducing costs, increasing the efficiency of clinics, enabling more effective booking, reducing mismatches between demand and capacity, and generally helping to increase productivity within healthcare.

SMS interventions have many benefits over alternative mediums. Firstly an SMS is cheap, roughly 3p per text whilst a letter can cost 10 times that. SMS is also capable of reaching the recipient wherever they are whilst letters can only be delivered to recipients last known address. This is particularly important, as people are more likely to retain their mobile numbers nowadays even if they change address, especially in London where the population is notoriously mobile. Mobile phone use is also ubiquitous in the UK, with a recent report estimating that over 99% of adults in London owned a mobile phone in 2013 (Ofcom, 2013). Another advantage of SMS is that there is evidence that people increasingly use electronic day planners and therefore a message direct to a person's phone encourages people to promptly record appointments and even allowing them to set alarms creating their own reminder. SMS interventions would therefore be as wide reaching as a postal intervention (if not more so) at a fraction of the cost and with greater accuracy.

Although previous evidence provides a sound rationale that SMS interventions have great potential for cervical screening, there is still a considerable amount of information required in order to introduce this intervention as standard practice.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
24 Years 至 64 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Women aged 24-64 years being invited for cervical screening during the course of the study. Women included in the study will be registered with a GP Practice that has agreed to participate in the trial.

排除标准

  • •Patients who opt-out, Patients who have had a hysterectomy, Patients who have informed GP practices of preference to not be screened, Patients Cervical cancer

研究组 & 干预措施

No intervention, 24-29 years

No Intervention

No intervention, group 24-29 years. Women will receive the written invitation to screening only

Messenger text message reminder, 24-29

Experimental

Messenger text message reminder, group 24-29 years.

干预措施: Messenger text message reminder (Other)

No intervention, 30-64 years

No Intervention

No intervention group 30-64 years, Women will receive the written invitation to screening only

Neutral text message reminder, 30-64

Experimental

Neutral Text message, group 30-64 years

干预措施: Neutral text message reminder (Other)

Messenger text message reminder, 30-64

Experimental

Messenger text message reminder, group 30-64

干预措施: Messenger text message reminder (Other)

Social Norms A reminder, 30-64

Experimental

Social Norms (population proportion) text message reminder, group 30-64 years

干预措施: Social Norms A reminder (Other)

Social Norms B reminder, 30-64

Experimental

Social Norms (population total) text message reminder, group 30-64 years

干预措施: Social Norms B reminder (Other)

Framed gain text reminder, 30-64

Other

Framed gain text message reminder, group 30-64 years

干预措施: Framed Gain text reminder (Other)

Framed loss text reminder, 30-64

Experimental

Framed loss text message reminder, group 30-64 years

干预措施: Framed Loss text reminder (Other)

结局指标

主要结局

Intention to treat analysis

时间窗: 13 months

Analysis of the rate of cervical screening by trial arm at the end of the screening round (32 weeks)

次要结局

  • Per protocol analysis using SMS delivery status data to compared the rate of cervical screening in women who receive the SMS at the end of the screening round (32 weeks from screening invitation)(13 months)
  • Attendance by age (control vs interventions)(13 months)
  • Attendance by level of deprivation (control vs interventions)(13 month)

研究者

发起方
Sarah Huf
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Sarah Huf

Clinical Research Fellow

Imperial College Healthcare NHS Trust

研究点 (1)

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