Treating affective disorders in patients with non-cardiac chest pai

Not Applicable

Completed

• Conditions: on-cardiac chest pain patients with a diagnosed panic and/or depressive disorder; Depressive episode, unspecified; Mental and Behavioural Disorders

• Registration Number: ISRCTN67858971
• Lead Sponsor: VU University Medical Center (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-10-10
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 117

Inclusion Criteria

1. All subjects aged 18 years or older who present themselves at the cardiac emergency unit of the VU University Medical Center with chest pain and are convinced they are experiencing a heart attack.
2. Full medical examination reveals no cardiopulmonary, gastrointestinal or endocrinal explanation for their complaints (and thus were diagnosed with 'non-cardiac chest pain')
3. Score 8 or higher on either or both subscales of the Hospital Anxiety and Depression Scale (HADS).
4. Meeting the DSM-IV criteria for panic disorder and/or depressive disorder
5. Providing signed informed consent after an oral and written explanation of the procedures and purpose of the study

Exclusion Criteria

1. Those with insufficient knowledge of the Dutch language
2. Those who, in the month before screening, received systematic psychotherapy or used antidepressants. Benzodiazepine usage is allowed during the trial, up to a maximum of 50 mg of oxazepam or equivalent doses of other medications.

Study & Design

• Study Type: Interventional
• Study Design: Not specified