To evaluate the effect of intravenous ondansetron on blood pressure and heart rate on using Propofol in adult patients undergoing operation under general anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/02/023497
- Lead Sponsor
- Maulana Azad Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiologists physical health status 1 and 2
Exclusion Criteria
1)Cardiorespiratory,renal,hepatic or thyroid disorders
2) Pregnant Patients
3) Patients with difficult airway.
4) History of allergy to study drug.
5) Patients taking selective serotonin re-uptake inhibitors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Incidence of hypotension in each group as determined by the number of patients( percentage) developing hypotension. <br/ ><br>2)Degree of hypotension in each group at various time intervals after propofol administration.Timepoint: every 1 minute for 10 minutes after administration of propofol
- Secondary Outcome Measures
Name Time Method Changes in heartrate in each groupTimepoint: before induction and then every 1 minute for 10 minutes after administration of propofol;post operative nausea and vomitingTimepoint: 1 hour after surgery;Total dose of propofol usedTimepoint: During induction og general anaesthesia;Total Mephentermine dose usedTimepoint: after induction with propofol