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临床试验/CTRI/2025/07/091634
CTRI/2025/07/091634尚未招募2 期

A clinical study to evaluate the efficacy of kushta Hajarul yahood in the management of Hasat e Mararah (cholelithiasis)

STATE TAKMEEL UT TIB COLLEGE AND HOSPITAL1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年8月4日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Discomfort in right hypochondrium

研究概览

简要总结

Dr. Nahid Anjum, a postgraduate scholar at the State Takmeel-ut-Tib College and Hospital, Lucknow, proposes a clinical study to evaluate the efficacy of a Unani formulation, Kushta Hajarul Yahood, in treating Hasat-e-Mararah (cholelithiasis or gallstones). The research is grounded in both Unani and modern medical understandings of gallstone pathology, aiming to provide an effective, economical, and non-surgical alternative to cholecystectomy. The study will involve 30 patients over 42 days in an open-label, single-arm clinical trial, with data collected through clinical symptoms and ultrasound imaging. Kushta Hajarul Yahood, a compound of Hajarul Yahood (Lapis Judaicus), Shorah Qalmi (Potassium Nitrate), and Aab-e-Mooli (Radish juice), is known in Unani literature for its lithotriptic, anti-inflammatory, and diuretic properties. Patients will be assessed based on symptomatic improvement and changes in stone size, while safety will be monitored through standard laboratory tests. The research seeks to validate traditional Unani treatments and offer relief to patients unwilling or unfit for surgery.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Cholelithiasis patients having symptoms and confirmed by USG Whole Abdomen Patients of both the sexes in between the age group of 20 to 60 years Patients with functioning gall bladder Consent of patient.

排除标准

  • Choledocolithiasis Ca Gallbladder Contracted gallbladder Shrinked gallbladder Thickened gallbladder Fibrosed gallbladder Mucocoele of gallbladder Pyocoele of gallbladder Obstructive Jaundice Stone size less than 15 mm Multiple stones Diabetes Mellitus Pregnancy and Lactation Mentally Retarded Patients.

结局指标

主要结局

Discomfort in right hypochondrium

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

Pain in right hypochondrium

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

Nausea and vomiting

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

Flatulent and dyspepsia

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

Tenderness (Right upper quadrant)

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

Referred pain to tip of right shoulder

时间窗: 0, 7th, 14th, 21st, 28th, 35th and 42nd day

次要结局

  • USG Whole Abdomen(0 and 42nd day)

研究者

发起方
STATE TAKMEEL UT TIB COLLEGE AND HOSPITAL
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

DR NAHID ANJUM

State Takmeel Ut Tib College And Hospital

研究点 (1)

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