Bacterial Reduction and Post Operative Pain After Cleaning and Shaping of Root Canals With Single File Systems Used in Different Kinematics
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Ain Shams University
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- post operative pain
Study Overview
Brief Summary
This study was conducted to compare the antibacterial effect and degree of postoperative pain of single rotary and reciprocating file systems during endodontic therapy
Detailed Description
Introduction
Instrumentation kinematic is one of the many aspects of shaping files that underwent heavy development through the last decade. The impact of the type of motion used to drive shaping instruments was heavily studied but mostly in-vitro. More randomized clinical trials are needed to achieve a reliable body of data concerning the issue.
Aim: This study aimed to evaluate the effect of varying shaping files' kinematics on bacterial reduction, post-operative pain and the incidence of flare-ups. Methods: Necrotic, asymptomatic, single-rooted mandibular premolars with single canals were used in the study, where 46 patients were randomly allocated to two groups. In the first group, WaveOne Gold was used for mechanical preparation while One Shape was used in the second group. Samples were taken preoperatively (S1) and after chemomechanical preparation (S2). Bacterial reduction was evaluated and compared between both groups via culturing technique and quantitative analysis by real-time polymerase chain reaction (qPCR). Post-operative pain and the incidence of flare-ups were also evaluated using the visual analog scale (VAS) method.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Masking Description
Sequentially generated numbers were placed in opaque envelopes until the intervention was conducted and each participant was asked to select an envelope that determine which group of intervention was assumed
Eligibility Criteria
- Ages
- 18 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •mandibular premolars
- •single rooted
- •single canalled
- •necrotic pulps
- •asymptomatic apical periodontitis
Exclusion Criteria
- •gross caries
- •root/crown fracture
- •sinus tract
- •intake of antibiotics within previous 3 months
- •pain with percussion
Arms & Interventions
rotation
root canal preparation performed using rotating instruments
Intervention: root canal shaping (Other)
reciprocation
root canal preparation performed using reciprocating instruments
Intervention: root canal shaping (Other)
Outcomes
Primary Outcomes
post operative pain
Time Frame: after the treatment visit by 72 hours
Visual analogue scale from 0-100 where 0 is the lowest and 100 is the highest
bacterial reduction
Time Frame: up to 1 hour
pre-instrumentation and post-instrumentation bacterial cultures to detect change in bacterial count after root canal instrumentation with the different kinematics
post operative pain
Time Frame: after the treatment visit by 24 hours
Visual analogue scale from 0-100 where 0 is the lowest and 100 is the highest
post operative pain
Time Frame: after the treatment visit by 48 hours
Visual analogue scale from 0-100 where 0 is the lowest and 100 is the highest
Secondary Outcomes
No secondary outcomes reported
Investigators
Shehab El Din Mohamed Saber
professor
Ain Shams University