A randomized controlled trial for the traditional Chinese medicine comprehensive antihypertensive ABC regimen in the treatment of grade-1 low- and intermediate-risk hypertensio
- Conditions
- Essential hypertension
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Aged between 18-65 years old, male or female;
(2) Diagnose with grade-1 essential hypertension, and the risk stratification is low-risk or intermediate-risk;
(3) The diagnosis of TCM syndrome is liver-yang syndrome or asthenic yin causing predominant yang syndrome, or no obvious syndrome;
(4) Those who have not taken antihypertensive drugs or have taken antihypertensive drugs irregularly, and do not want to take antihypertensive drugs in the next three months;
(5) Subjects are volunteered to participate in the trial and signed the informed consent.
(1) Obvious liver and kidney dysfunction. ALT, AST, BUN or creatinine is more than 2 times higher than normal;
(2) Those who cannot operate Baduanjin or acupoint massage independently;
(3) Those who have eczema or injury in head, neck or ear, which may be unsuitable for acupoint massage;
(4) Chronic gastrointestinal diseases;
(5) Those who may have poor compliance and failure to follow up on time;
(6) Woman during pregnancy or lactation or those who have a recent birth plan;
(7) Patients with severe mental illness, malignant tumors or other major diseases;
(8) Those with a reversed lifestyle or irregular sleep pattern;
(9) Those who are known or suspected to be allergic to the test drug;
(10) Those who practice traditional Chinese exercises (such as Taijiquan, Ba Duanjin, etc.) in the past 3 months;
(11) Those who are inappropriate to participate in this research.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24 hours average blood pressure;
- Secondary Outcome Measures
Name Time Method home blood pressure;Symptom score of hypertension grading quantization table;WHOQOL-BREF score;office blood pressure;daytime mean systolic blood pressure (dSBP), nighttime mean systolic blood pressure (nSBP),;24-hour average heart rate;Compliance rate of office blood pressure;