Effects of Transcatheter Aortic Valve Implantation on Left Ventricular Function And Coronary Hemodynamics

Completed

• Conditions: aortic valve narrowing; aortic valve stenosis; 10046973

• Registration Number: NL-OMON39853
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

transfemoral transcatheter aortic valve implantation

Exclusion Criteria

coronary arteries considered unsuitable by treating interventional cardiologist.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The short and long term change in left ventricular function after transcatheter<br /><br>aortic valve implantation, measured invasively by means of PV-loops and<br /><br>non-invasively with echocardiography and cardiac CT and MRI.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameters compared with baseline and, where possible,<br /><br>compared between the TAVI and SAVR are: invasively measured LV systolic and<br /><br>diastolic properties, coronary flow characteristics, LV ejection fraction, LV<br /><br>mass, LV myocardial perfusion, flow properties across the aortic valve,<br /><br>presence/amount of aortic and mitral regurgitation, right ventricular function,<br /><br>cardiac conduction, mortality and morbidity, NYHA functional class and quality<br /><br>of life. </p><br>