Assessment of Colchicine efficacy in treatment of chronic hepatitis B
Phase 3
- Conditions
- Chronic viral hepatitis B.Chronic viral hepatitis BB 18.1
- Registration Number
- IRCT138807112539N1
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
positive HBS Ag, confirmed chronic hepatitis B, ALT level at least twofold of normal range
Exclusion criteria: positive HCV Ab, positive HIV Ab, Alcohol abuse, Presence of auto immune hepatitis, metabolic liver disease, right cardiac failure or pulmonary hypertension, low compliance, allergic reaction to drugs or sever side effect of drugs, presence of decompensate cirrhosis (PT>20 sec and ALb<3 gr/dl)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment of chronic hepatitis B. Timepoint: One month before intervention and one month after intervention. Method of measurement: Laboratory measurement of serum ALT- Albumin-bilirubin and PT.
- Secondary Outcome Measures
Name Time Method