IRCT138807112539N1
Completed
Phase 3
A comparative evaluation of combination therapy of Lamivudine and Colchicine comparing with Lamivudine and placebo in clinical and laboratory improvement of chronic hepatitis B
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Arak University of Medical Sciences
- Enrollment
- 100
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •positive HBS Ag, confirmed chronic hepatitis B, ALT level at least twofold of normal range
- •Exclusion criteria: positive HCV Ab, positive HIV Ab, Alcohol abuse, Presence of auto immune hepatitis, metabolic liver disease, right cardiac failure or pulmonary hypertension, low compliance, allergic reaction to drugs or sever side effect of drugs, presence of decompensate cirrhosis (PT\>20 sec and ALb\<3 gr/dl)
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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