Potential Health Effects of Aronia Intake
- Conditions
- Health Effects of Aronia
- Interventions
- Dietary Supplement: Aronia, washout and then placeboDietary Supplement: Placebo, washout and then aronia
- Registration Number
- NCT03405753
- Lead Sponsor
- Odense University Hospital
- Brief Summary
Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months. The potential health effects are investigated. Following parameters are measured before and after each period of tablet intake: 1) Blood pressure, 2) Lipid fractions, 3) Testosterone, 4) Phase II markers, 5) HbA1c, 6) HSCRP, 7) F2-isoprostanes, and 8) semen quality.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 109
- Healthy men with total cholesterol between 5 and 7 mmol/L, who do not take medication
- Chronic diseases and intake of medication or antioxidants
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Aroia Placebo, washout and then aronia - Placebo Placebo, washout and then aronia - Placebo Aronia, washout and then placebo - Aroia Aronia, washout and then placebo -
- Primary Outcome Measures
Name Time Method Cholesterol 9 months HDL, LDL and total cholesterol in mmol/L
- Secondary Outcome Measures
Name Time Method Semen quality 9 months DNA fragmentation in percent
Blood pressure 9 months Systolic and diastolic blood pressure in mmHg
Phase II enzyme activity 9 months Catalase (CAT) in U/mL
Isoprostanes 9 months Peroxidation of fatty acids measured in U/mL
High Sensitivity C reactive protein 9 months Acute phase reactant in mg/L
Trial Locations
- Locations (1)
Centre of Andrology & Fertility Clinic, Department D, Odense University Hospital
🇩🇰Odense, Denmark