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Potential Health Effects of Aronia Intake

Not Applicable
Completed
Conditions
Health Effects of Aronia
Interventions
Dietary Supplement: Aronia, washout and then placebo
Dietary Supplement: Placebo, washout and then aronia
Registration Number
NCT03405753
Lead Sponsor
Odense University Hospital
Brief Summary

Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months. The potential health effects are investigated. Following parameters are measured before and after each period of tablet intake: 1) Blood pressure, 2) Lipid fractions, 3) Testosterone, 4) Phase II markers, 5) HbA1c, 6) HSCRP, 7) F2-isoprostanes, and 8) semen quality.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
109
Inclusion Criteria
  • Healthy men with total cholesterol between 5 and 7 mmol/L, who do not take medication
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Exclusion Criteria
  • Chronic diseases and intake of medication or antioxidants
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
AroiaPlacebo, washout and then aronia-
PlaceboPlacebo, washout and then aronia-
PlaceboAronia, washout and then placebo-
AroiaAronia, washout and then placebo-
Primary Outcome Measures
NameTimeMethod
Cholesterol9 months

HDL, LDL and total cholesterol in mmol/L

Secondary Outcome Measures
NameTimeMethod
Semen quality9 months

DNA fragmentation in percent

Blood pressure9 months

Systolic and diastolic blood pressure in mmHg

Phase II enzyme activity9 months

Catalase (CAT) in U/mL

Isoprostanes9 months

Peroxidation of fatty acids measured in U/mL

High Sensitivity C reactive protein9 months

Acute phase reactant in mg/L

Trial Locations

Locations (1)

Centre of Andrology & Fertility Clinic, Department D, Odense University Hospital

🇩🇰

Odense, Denmark

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