Congenital Lung Abnormalities on MRI

Completed

• Conditions: congenital cystic lung disease; Congenital pulmonary airway malformation; 10038686; 10010613

• Registration Number: NL-OMON50335
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 18

Inclusion Criteria

- Radiological or if resected pathological diagnosis of CPAM
- Enrolment in CHIL follow-up program
- Age * 8 years and < 18 years at the start of the study
- Signed informed consent by parents and/or patient

Exclusion Criteria

- Contra- indications for MRI
- Cognitive impairment preventing adherence to breathing instructions
- Presence of associated anomalies in chest cavity which might skew results
according to primary physician
- Claustrofobia

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoints are the MRI features of the lungs both before and<br /><br>after resection of CPAM and its correlation to lung function. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoint is the MRI scan protocol in which optimal imaging of lung<br /><br>parenchyma and abnormalities is achieved. Furthermore, the difference in lung<br /><br>function between surgically and conservatively treated patients as well as<br /><br>their relation to imaging characteristics including volume of the abnormality. </p><br>