Clinical Profiles and Outcomes of Acute Aortic Dissection in the Chinese Patients

Completed

• Conditions: Aorta Thoracic Ascending Dissection; Dissection of Descending Aorta

• Registration Number: NCT01606943
• Lead Sponsor: Xijing Hospital

Brief Summary

Clinical profiles and outcomes of patients with acute aortic dissection have not yet been evaluated in China. The aim of this study is to establish clinical registry of acute aortic dissection in China and to analyze clinical features, managements and outcomes of Chinese patients with acute aortic dissection.

Detailed Description

In 1996, the Internation Registry of Acute Aortic Dissection(IRAD) was established to improve clinical diagnosis and treatment of acute aortic dissection. However, most patients from the IRAD are Caucasian. These data were not sufficient to reflect clinical profiles and outcomes of Chinese patients with acute aortic dissection. In China, little is known about clinical features, managements and outcomes of acute aortic dissection involving a large number of patients. The investigators established clinical multicenter registry of acute aortic dissection. Between January 2009 and February 2012, about 2000 were enrolled in the Chinese registry of acute aortic dissection(CRAD) database. The aim of this study is to analyze clinical profiles and outcomes of Chinese patients with acute aortic dissection.

Study Timeline

• Study Start: 2009-01
• Primary Completion: 2012-02
• Study Completion: 2012-02
• Study First Submitted: 2012-03-01
• Status Verified: 2012-05
• Study First Submitted QC: 2012-05-25
• Last Update Submitted: 2012-05-25
• Study First Posted: 2012-05-28
• Last Update Posted: 2012-05-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Stanford type A dissection
• Stanford type B dissection
• Retrograde Stanford Type B dissection
• Unclassified dissection with primary tear located in the aortic dissection

Exclusion Criteria

• Aortic aneurysm
• Active infection or active vasculitides
• Myocardial infarction or Cerebral accident within 2 months
• Unwillingness to cooperate wiht study procedures or follow-up visits

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Xijing Hospital; 🇨🇳 Xi'an, Shaanxi, China