Intravenous midazolam-droperidol (combination), droperidol (only) or olanzapine (only) for the acutely agitated patient:A multi-centre, randomised, double-blind, controlled, clinical trial

Phase 4

Completed

• Conditions: severe agitation; aggression; Mental Health - Other mental health disorders

• Registration Number: ACTRN12614000980639
• Lead Sponsor: Austin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-09-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 342

Inclusion Criteria

Emergency Department patients aged 18-65 years who require IV drug sedation for acute agitation

Exclusion Criteria

1. known hypersensitivity or contraindication to the study drugs
2. reversible aetiology for agitation (hypotension, hypoxia, hypoglycaemia)
3. known pregnancy
4. acute alcohol withdrawal (particularly amenable to benzodiazepines alone)

Study & Design

• Study Type: Interventional
• Study Design: Not specified