To evaluate the efficacy of a moisturizing cream in the treatment of Eczema.

Completed

• Conditions: Other and unspecified dermatitis,

• Registration Number: CTRI/2021/06/034406
• Lead Sponsor: Dr Reddys Laboratories Ltd

Brief Summary

**Day 0**

- Explanation of the Study and procedures.

- Collection of Informed consent

- Selection of volunteers by Inclusion/ exclusion criteria.

- Participants will be randomized into 2 groups based on their EASI scores - One group will get prescribed treatment with moisturizing cream and other group will get only prescribed treatment without any moisturizing cream.

- Baseline EASI scores

- Instrumental readings using MMSC and VapoMeter

- Administration of  self-assessment questionnaire to evaluate itching and burning sensation.

**Week 2 and Week 4**

- Same parameters as mentioned above were measured.

- Products were retrieved from the participants.

Conclusion:

When compared to baseline, Venusia Max Cream used as an adjuvant along with standard

treatment significantly reduced the EASI score, significantly increased the skin hydration

measured by MMSC and significantly reduced the trans epidermal water loss measured by

VapoMeter. It also significantly showed reduction in 5D pruritus and burning sensation in

self-assessment score.

Clinical dryness self-assessment score has been done using a binary scale. There was no

change in dryness perception by the participants in both the groups after the treatment.

Also, Venusia Max Cream improved the skin hydration significantly on Eczematous skin of

patients and significantly reduced the 5D Pruritis score compared to the group where

Venusia Max Cream was not used as an adjuvant along with standard treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-28
• Study Completion: 2021-12-15
• Last Update Posted: 2022-03-03

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Voluntary men and women with Atopic Dermatitis, Eruptive Eczema, Chronic Lichenified Eczema, Lichen Simplex Chronicus, Discoid Eczema, Allergic Eczema, with EASI scores 8 -21 or more.

Exclusion Criteria

• Pregnant women by UPT, Lactating mothers Participants with dry skin.
• Localised psoriasis patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical evaluation	Day 0, Week 2, Week 4
Instrumental evaluation for Skin Hydration and Trans epidermal water loss	Day 0, Week 2, Week 4
Self-Assessment (cutaneous dryness, Itching, Burning)	Day 0, Week 2, Week 4

Trial Locations

Locations (1)

Skin Clinic; 🇮🇳 Nashik, MAHARASHTRA, India

Skin Clinic

🇮🇳Nashik, MAHARASHTRA, India

Dr Suneel Vartak

Principal investigator

suneel.vartak@gmail.com