Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil followed by chemoradiotherapy concurrent with fractionated administration of high-dose cisplatin for patients with locally advanced squamous cell carcinoma of the head and neck
Phase 2
- Conditions
- ocally advanced head and neck cancer
- Registration Number
- JPRN-UMIN000024686
- Lead Sponsor
- ational Cancer Center Hospital East
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Not provided
Exclusion Criteria
Active bacterial or fungus infection Active Malignant disease, other than that being treated in this study Pregnant or lactating women Clinically significant and/or uncontrolled heart disease History of cerebrovascular disease Uncontrolled diabetes or hypertension Severe complications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility of TPF
- Secondary Outcome Measures
Name Time Method overall response rate to TPF local recurrence-free survival progression-free survival overall survival safety profile