MedPath

Short Term Feeding for Asian Patients With Liver Cirrhosis

Not Applicable
Completed
Conditions
CIRRHOSIS
Interventions
Dietary Supplement: Osmolite and B.C.A.A.
Dietary Supplement: Normal oral intake & supplementation if necessary
Registration Number
NCT01165073
Lead Sponsor
University of Malaya
Brief Summary

The benefits of short-term naso-gastric feeding in patients with advanced cirrhosis remain uncertain. This was a randomised study comparing naso-gastric feeding and oral feeding in Asian patients with cirrhosis who were admitted to hospital for decompensation.

Detailed Description

Consecutive patients with decompensated cirrhosis who fitted the inclusion criteria, will be randomised to either naso-gastric or oral feeding. Total feeding will be for 2 weeks only. Following intervention specific nutritional and liver-related parameters will be measured during the 2 weeks and up to 6 weeks later. Comparison between both groups will then be made.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
52
Inclusion Criteria
  • Patients with decompensated cirrhosis of any etiology.
Exclusion Criteria
  • Advanced hepatic encephalopathy,
  • Variceal bleeding,
  • Hepatocellular carcinoma.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Naso-gastric tube feedingOsmolite and B.C.A.A.-
Oral feedingNormal oral intake & supplementation if necessary-
Primary Outcome Measures
NameTimeMethod
Improvement in Child-Pugh scoreUp to 6 weeks

Change in the Child-Pugh score, assessing liver damage in cirrhosis

Secondary Outcome Measures
NameTimeMethod
Improvement in nutritional parametersup to 6 weeks

Improvement in nutritional anthropometry and assessment tool markers after intervention

Trial Locations

Locations (1)

University of Malaya Medical Centre

🇲🇾

Kuala Lumpur, Federal Territory, Malaysia

© Copyright 2025. All Rights Reserved by MedPath