Short Term Feeding for Asian Patients With Liver Cirrhosis
- Conditions
- CIRRHOSIS
- Interventions
- Dietary Supplement: Osmolite and B.C.A.A.Dietary Supplement: Normal oral intake & supplementation if necessary
- Registration Number
- NCT01165073
- Lead Sponsor
- University of Malaya
- Brief Summary
The benefits of short-term naso-gastric feeding in patients with advanced cirrhosis remain uncertain. This was a randomised study comparing naso-gastric feeding and oral feeding in Asian patients with cirrhosis who were admitted to hospital for decompensation.
- Detailed Description
Consecutive patients with decompensated cirrhosis who fitted the inclusion criteria, will be randomised to either naso-gastric or oral feeding. Total feeding will be for 2 weeks only. Following intervention specific nutritional and liver-related parameters will be measured during the 2 weeks and up to 6 weeks later. Comparison between both groups will then be made.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
- Patients with decompensated cirrhosis of any etiology.
- Advanced hepatic encephalopathy,
- Variceal bleeding,
- Hepatocellular carcinoma.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Naso-gastric tube feeding Osmolite and B.C.A.A. - Oral feeding Normal oral intake & supplementation if necessary -
- Primary Outcome Measures
Name Time Method Improvement in Child-Pugh score Up to 6 weeks Change in the Child-Pugh score, assessing liver damage in cirrhosis
- Secondary Outcome Measures
Name Time Method Improvement in nutritional parameters up to 6 weeks Improvement in nutritional anthropometry and assessment tool markers after intervention
Trial Locations
- Locations (1)
University of Malaya Medical Centre
🇲🇾Kuala Lumpur, Federal Territory, Malaysia