Short Term Feeding for Hospitalised Asian Patients With Liver Cirrhosis - a Randomised Trial of Naso-gastric vs Oral Feeding
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Improvement in Child-Pugh score
研究概览
简要总结
The benefits of short-term naso-gastric feeding in patients with advanced cirrhosis remain uncertain. This was a randomised study comparing naso-gastric feeding and oral feeding in Asian patients with cirrhosis who were admitted to hospital for decompensation.
详细描述
Consecutive patients with decompensated cirrhosis who fitted the inclusion criteria, will be randomised to either naso-gastric or oral feeding. Total feeding will be for 2 weeks only. Following intervention specific nutritional and liver-related parameters will be measured during the 2 weeks and up to 6 weeks later. Comparison between both groups will then be made.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with decompensated cirrhosis of any etiology.
排除标准
- •Advanced hepatic encephalopathy,
- •Variceal bleeding,
- •Hepatocellular carcinoma.
研究组 & 干预措施
Naso-gastric tube feeding
干预措施: Osmolite and B.C.A.A. (Dietary Supplement)
Oral feeding
干预措施: Normal oral intake & supplementation if necessary (Dietary Supplement)
结局指标
主要结局
Improvement in Child-Pugh score
时间窗: Up to 6 weeks
Change in the Child-Pugh score, assessing liver damage in cirrhosis
次要结局
- Improvement in nutritional parameters(up to 6 weeks)