Effect of Regional Versus General Anesthesia on Thirty-day Outcomes Following Carotid Endarterectomy: a Matched-pairs Cohort Study.
- Conditions
- Regional Anesthesia MorbidityCarotid Artery DiseasesPerioperative/Postoperative Complications
- Registration Number
- NCT05706688
- Lead Sponsor
- University of Virginia
- Brief Summary
The goal of this observational study is to assess the effect of regional versus general anesthesia on carotid endarterectomy thirty-day outcomes. The main questions it aims to answer are:
* Is regional anesthesia associated with lower incidence of major morbidity and mortality?
* Is regional anesthesia associated with lower incidences of secondary adverse events?
Participants will be sampled from the 2015-2019 American College of Surgeons National Surgical Quality Improvement Program
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 37204
- Elective, non-emergent cases
- Regional anesthesia
- General anesthesia
- Concurrency in procedures
- Acute kidney injury (preoperative)
- End-stage renal disease (preoperative)
- Metastatic disease (preoperative)
- Wound infection (preoperative)
- Sepsis (preoperative)
- ASA 5
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major morbidity and mortality Thirty days Stoke, myocardial infarction, or death
- Secondary Outcome Measures
Name Time Method Bleeding events Thirty days Requiring transfusion
Minor morbidity Thirty days Reintubation, prolonged (\>48 hour) ventilator dependence, pneumonia, deep venous thrombosis, pulmonary embolism, superficial surgical site infection (SSI), deep incisional SSI, organ space SSI, wound dehiscence, sepsis, septic shock, acute kidney injury, and progressive renal insufficiency
Unplanned resource utilization Thirty days Unplanned readmission and unplanned reoperation
Mortality Thirty days Mortality