Computerised Assistance of Cardiovascular Monitoring in Intensive Care

Recruiting

• Conditions: Cardiovascular dysfunction; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system; Cardiovascular - Coronary heart disease; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12611001197921
• Lead Sponsor: niversity of Canterbury

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-11-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

Post-cardiac surgery or diagnosed CVS dysfunction as leading contributor to ICU admission; Arterial and central venous catheterization; and full or intermittent mechanical ventilation (intubated).

Exclusion Criteria

Moribund or not expected to survive 48 hours; patient not intubated or does not have required catheters for measurements.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the ability of the model-based method to retrospectively track hemodynamic changes resulting from the inotropic and PEEP interventions. The model-based results will be compared to clinical diagnoses, clinically derived CVS performance metrics, and standard ICU hemodynamic measurements. Where applicable, the ability of the model to capture the data will be analysed by 90% confidence intervals of the absolute percentage error between the identified model predictions and the measured response. Errors within measurement error of 10% will be assumed to be a fully accurate prediction.[The outcomes of the trials will be assessed at the end of the clinical study.]

Secondary Outcome Measures

Name	Time	Method
To store all the hemodynamic measurements recorded in the ICU including: arterial pressure, central venous pressure, pulmonary artery pressure, stroke volume, global end diastolic volume, extra-vascular lung water, heart rate, respiratory pressure and flow, ECG, and other available cardiac and circulatory measurements to create a virtual patient database for future research.[The database will be set up at the end of the study.]