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ow-dose Atropine for the prevention of nearsightedness in Danish Childre

Phase 1
Conditions
Childhood myopia
MedDRA version: 20.0Level: LLTClassification code 10036803Term: Progressive high (degenerative) myopiaSystem Organ Class: 100000004853
Therapeutic area: Body processes [G] - Biological Phenomena [G16]
Registration Number
EUCTR2018-001286-16-DK
Lead Sponsor
Rigshospitalet
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
150
Inclusion Criteria

Children aged =6-<9 years: myopia =-1 (spherical equivalent) in at least one eye
Children aged =9-=12 years: myopia =-2 (spherical equivalent) in at least one eye
Cylinder less than 1.5 diopters

Are the trial subjects under 18? yes
Number of subjects for this age range: 150
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Myopia related to retinal dystrophies
Collagen syndroms (Ehlers-Danlos syndrome, Marfan syndrome and Stickler syndrome)
Other ocular pathology (e.g., amblyopia, strabismus)
Previous eye surgery
Previous use of agents thought to affect myopia progression, e.g. atropine, pirenzepine or 7-methylxanthine (metabolite of caffeine and theobromine) and orthokeratology contact lenses
Known allergy to atropine or any of the contents of the trial medication (active and in-active ingredients) used in the study
Non-compliance to eye examinations
Serious systemic health troubles (e.g., cardiac or respiratory illness) and developmental disorders and delays

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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