The Effects of an Intensive Lifestyle Intervention for Type 2 Diabetes on Employment, Earnings, and Retirement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,091
- 主要终点
- Employed (any earnings from employment or self-employment) by study year (all study participants)
研究概览
简要总结
Starting in 2001, the Look AHEAD study randomized patients with type 2 diabetes to an intensive lifestyle intervention (ILI) focused on weight loss versus a control group receiving diabetes education ("Diabetes Support and Education," or DSE). The ILI successfully reduced weight, improved diabetes control, and functional status, among other outcomes. In this study, the investigators will compare employment, earnings, and retirement between the ILI and the control group during and after the intervention period (2001-2018).
详细描述
Starting in 2001, the Look AHEAD study randomized 5145 patients with type 2 diabetes to an intensive lifestyle intervention (ILI) focused on weight loss versus a control group receiving diabetes education ("Diabetes Support and Education," or DSE).The Look AHEAD study tested whether participants with type 2 diabetes assigned to an intensive lifestyle intervention (ILI) for weight loss exhibited reductions in cardiovascular morbidity and mortality, relative to a control group receiving usual care and diabetes support and education. During the 12-year intervention period, the ILI led to persistent reductions in weight, waist circumference, and hemoglobin A1c and improvements in physical fitness, among other clinical benefits. After the conclusion of the intervention in 2012, participants were consented to be linked with administrative data. The investigators attempted to link 3188 consenting participants with Social Security Administration databases. Of these, the investigators were able to successfully link 3093 participants. In this study, the investigators will compare employment, earnings, and retirement between the ILI and the control group during and after the intervention period (2001-2018). The investigators will determine ILI-versus-control differences in employment, earnings, and retirement in each year after randomization, relative to a pre-randomization assessment period. The investigators will also investigate ILI-versus-control differences in cumulative years of employment and earnings after randomization which occurred between 2001-2004. The investigators will use multivariate regressions controlling for baseline participant characteristics and clinic site and also survival analyses that estimate whether the time until retirement differs between the ILI and control groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Look AHEAD participation: met age requirements and other criteria at time of study enrollment which occurred between 2001-2004 (as noted in Look AHEAD Research Group (2013))
- •Consented to administrative data linkages
- •Provided individual identifiers that could be linked with Social Security Administration databases
- •Were successfully linked to Social Security Administration data
排除标准
- 未提供
结局指标
主要结局
Employed (any earnings from employment or self-employment) by study year (all study participants)
时间窗: 12-month intervals relative to randomization occurring between 2001-2018
This measure is based on Social Security Administration data on earnings
Total earnings from employment and/or self-employment by study year (all study participants)
时间窗: 12-month intervals relative to randomization occurring between 2001-2018
This measure is based on Social Security Administration data on earnings; earnings for unemployed study participants will be captured as zeros.
次要结局
- Total person-years employed since randomization (all study participants)(From initial randomization (occurred between 2001-2004) through 2018)
- Ever received Supplemental Security Income (SSI) benefits at age 65 since randomization (all study participants)(From initial randomization (occurred between 2001-2004) through 2018)
- Total person-years from randomization to retirement (all study participants)(From initial randomization (occurred between 2001-2004) through 2018)
- Total earnings from employment and/or self-employment by study year (excluding unemployed study participants)(12-month intervals relative to randomization occurring between 2001-2018)
- Ever employed (any earnings from employment or self-employment) after randomization (all study participants)(From initial randomization (occurred between 2001-2004) through 2018)
- Retired (any Social Security retirement entitlement/election) by study year (all study participants)(12-month intervals relative to randomization occurring between 2001-2018)
- Total earnings from employment and/or self-employment since randomization (all study participants)(From initial randomization (occurred between 2001-2004) through 2018)