Financial Incentives and Recruitment to the APT Webstudy

Not Applicable

Recruiting

• Conditions: Alzheimer Disease; Dementia; Prodromal Alzheimer's Disease; Preclinical Alzheimer's Disease
• Interventions: Behavioral: Message; Behavioral: Financial Incentives

• Registration Number: NCT06033066
• Lead Sponsor: University of Southern California

Brief Summary

This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-09
• Study First Submitted QC: 2023-09-07
• Study First Posted: 2023-09-13
• Study Start: 2023-09-27
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-19
• Last Update Posted: 2023-12-28
• Primary Completion: 2026-03
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 48000

Inclusion Criteria

To be eligible to participate in this study, an individual must meet all of the following criteria:

• Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers.
• Age 50 or older
• Literate in either English or Spanish

Exclusion Criteria

• Below age 50
• Documentation of prior dementia diagnosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Messaging Only	Message	16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.
Small Incentive	Financial Incentives	16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.
Prize Incentive	Financial Incentives	16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.

Primary Outcome Measures

Name	Time	Method
Enrollment status into the APT Webstudy	2-weeks	APT Webstudy enrollment rate based on completion of at least one of the two APT Webstudy cognitive assessments (Cognitive Function Instrument \[CFI\] and/or Cogstate Brief Battery).

Secondary Outcome Measures

Name	Time	Method
Cost per enrollee	annual	Cost to acquire an enrollment
Completion of cognitive assessments within the APT Webstudy	2-weeks	Completion of both APT Webstudy cognitive assessments (Cognitive Function Instrument \[CFI\] and/or Cogstate Brief Battery).

Trial Locations

Locations (1)

Contra Costa Health Plan; 🇺🇸 Martinez, California, United States