Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 24
- Primary Endpoint
- Dyspnea
Overview
Brief Summary
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
Detailed Description
Nasal stimulation is generated by breathing, which enables olfaction and helps to rhythm brain activity. The loss of nasal stimulation in tracheotomized patients who are dependent on mechanical ventilation may negatively affect respiratory drive and contribute to dyspnea. Restoring nasal airflow therefore emerges as an attractive non-pharmacological approach to treat dyspnea in patients undergoing mechanical ventilation weaning.
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age ≥ 18 years
- •Tracheostomy and mechanical ventilation
- •Consent to participate
- •Affiliation to health insurance
Exclusion Criteria
- •Agitation, delirium
- •Continuous use of sedatives
- •Patients under law protection
- •Patients without health insurance
- •Breastfeeding and pregnancy
Arms & Interventions
Patients ventilated
Baseline ventilator settings under pressure support
Intervention: Baseline (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
Intervention: Installation of high flow humidified air cannula (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
Intervention: Nasal air puffs (Procedure)
Patients ventilated
Baseline ventilator settings under pressure support
Intervention: propeller fan (FAN) (Procedure)
Outcomes
Primary Outcomes
Dyspnea
Time Frame: minute 20
visual analogical scale
Secondary Outcomes
- airway occlusion pressure(minute 20)
- end expiratory occlusion pressure(minute 20)
- respiratory electromyogram (EMG)(minute 20)
- tolerance(minute 20)